01/07/2023
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Maddison's Ongoing Support: Collaborating with Cardiff University and Bill & Melinda Gates Foundation to Develop an Innovative Contraception Solution. 

Innovative microneedle technology is being developed as an effective, pain-free and discreet method of delivering contraception across the world’s poorest countries, thanks to a new research consortium led by Cardiff University and supported by the Bill & Melinda Gates Foundation.

 

Microneedle development for the worlds most vulnerable women

The project is focued on pre-clinical work to develop microneedle patches that have the potential to be painlessly and inconspicuously administered by the user themselves within a few seconds and can last for up to six months. This new method of contraception would meet the needs of some of the world’s poorest and most vulnerable women.

Cardiff University’s School of Pharmacy and Pharmaceutical Sciences and School of Engineering have secured funding for the ambitious project that brings together additional expertise of partners from academia (Edinburgh University), industry (InnoCore Pharmaceuticals, Maddison Product Design, Isca Healthcare, REMEDI), NGOs (Population Council, PATH), partnerships (Hub Cymru Africa), charitable bodies (Knowledge For Change, Life for African Mothers) and NHS Trusts.  


 

Voluntary family planning is something that many of us take for granted but in some of the poorest countries women and girls don’t have this choice.
Professor James Birchall, from Cardiff University’s School of Pharmacy and Pharmaceutical Sciences
compliance and testing by Maddison for Cardiff University

According to the World Health Organization, ‘214 million women of reproductive age in developing countries who want to avoid pregnancy are not using a modern contraceptive method’. Better access to contraceptives and voluntary family planning would result in fewer unintended pregnancies, fewer women and girls dying during pregnancy and childbirth, and fewer infant deaths.
Additionally, empowering women and girls to make their own choices about if, and when, they have children would vastly improve their educational and economic opportunities, as well as leading to healthier families and communities.

However, there are many socio-economic and cultural barriers preventing women from obtaining contraception even when they want to plan or prevent pregnancy. There may be a lack of awareness of the risk of becoming pregnant, and some may be deterred by the cost, inconvenience or concerns about side effects and many simply can’t physically access effective methods of contraception.

The Bill & Melinda Gates Foundation is funding research in a bid to address these issues and to develop practical and effective methods of contraception that are centred around the needs of the user. The grant will allow the consortium to assess the technical feasibility, usability and acceptability of the self-administrable contraceptive microneedle patch for use in the countries that need it most.  

If successful, the program will lead to an affordable long-acting contraceptive that combines easy and painless self-administration with full bioresorption, thereby avoiding the need for removal surgery.